5-OMe UTP, 200mM Tris Salt Solution Grade:M (Molecular Biology)+S (Endotoxin)

5-OMe UTP, 200mM Tris Salt Solution Grade:M (Molecular Biology)+S (Endotoxin)5 methoxy uridine 5 triphosphate (5moUTP) is a chemically modified uridine nucleotide designed for enzymatic incorporation into RNA during IVT using RNA polymerases such as T7 RNA polymerase. RNAs containing 5moU have been shown to exhibit reduced innate immune activation and altered translational properties compared with unmodified uridine. This product is supplied as a 200 mM aqueous solution in the Tris salt form, providing a stable, mildly

"Inhibition of human telomerase by 2′-O-methyl-RNA

enzyme kinetics

reduces immunogenicity

or 10 min at 65 °C in AMA (ammonia/methylamine

9 (2003): 1034-1048

a cyanoethyl (CE) protecting group on phosphite

In vitro transcription for synthesis of mRNA

[2] Maracci

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Probing and diagnostics

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Compatibility: Can be used alongside modified phosphoramidites (e